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Research report · 16 October 2026

Charles River Laboratories International, Inc. (CRL)

Health Care · Life Sciences Tools & Services · US stock · price as of 16 Oct 2026

Key indicators

Price$300.15
52-week range$146.20 – $333.30
Market cap$14.4B
P/E (trailing)–
EV / EBITDA43.4×
Free-cash-flow yield2.6%
Dividend yield–
Revenue (last 12 months)$4.0B
Revenue growth (3y a year)0.3%
Operating margin2.3%
Return on invested capital1.4%
Net debt / EBITDA6.3×

Fair value

Blended fair value$168.66 range $169 – $169
Versus priceOvervalued−44% to fair value
Peer multiples$168.66
10-year DCF (market-scaled)n/m
Earnings power value (floor, not blended)$24.84
Model uncertaintyMedium

X-Ray Score

22/ 100 · Medium confidence · ahead of 2% of sector peers
Valuation15
Growth23
Profitability33
Financial health14
Dividends–

Five-year price chart navy: price · brown: 200-day average · blue band: fair value range

78.81177274372470Fair value $1692021-102023-012024-042025-072026-10

Executive summary

Charles River Laboratories supports drug development with research models, preclinical services and manufacturing support. It breeds laboratory research animals, carries out discovery and safety assessment studies for drug candidates, and supplies testing and related services for the manufacture of biologic products. Customers are pharmaceutical and biotechnology companies, along with academic and government researchers. The business is organised into groups for research models, discovery and safety assessment, and manufacturing solutions.

Revenue of $4.0 billion over the last twelve months comes from research models and from fees for contract research and testing work. Revenue has grown at 0.3% a year across the last three years. The operating margin is 2.3%, the business earns 1% on the capital invested in it, and net debt is 6.3 times EBITDA. No dividend is paid.

StocksXray gives Charles River Laboratories International, Inc. an X-Ray Score of 22 out of 100 (medium confidence), ahead of 2% of the S&P 500 stocks in its sector. Its strongest lens is profitability (33) and its weakest is financial health (14).

Our fair value blend is $168.66 (range $168.66 to $168.66). At $300.15 the stock trades 78% above that blend, so the label is "Overvalued" with medium model uncertainty. Fair value is a range, not a price target.

stocksxray.com · page 1
XStocksXray
Charles River Laboratories International, Inc. (CRL)

Valuation history multiples at each fiscal year-end price; the last column uses today's price and the last twelve months

FY2021FY2022FY2023FY2024FY2025Now
Price$369.20$217.90$236.40$186.16$203.66$300.15
Market cap$19.0B$11.2B$12.2B$9.6B$10.1B$14.4B
P/E48.6×23.0×25.6×930.8×––
EV / revenue6.0×3.4×3.5×2.9×3.0×4.2×
EV / EBITDA25.0×14.3×15.6×19.8×28.1×43.4×
Price / free cash flow35.7×37.9×33.3×19.2×19.5×38.9×
Free-cash-flow yield2.8%2.6%3.0%5.2%5.1%2.6%
Price / book7.5×3.8×3.4×2.8×3.2×5.1×
Dividend yield––––––

Fundamentals checklist ● 2 Good · ● 1 Average · ● 11 Bad · each check graded against the sector

Cash quality

Earnings backed by cash−10.9%Good
Free-cash-flow yield2.6%Bad

Risk models

Altman Z score1.7×Bad
Piotroski F-Score4 of 9Bad

Growth

Free-cash-flow growth (3y)20.7%Good
Revenue growth (3y)0.3%Bad
Growth consistency20%Bad

Balance sheet

Current ratio1.3×Average
Net debt / EBITDA6.3×Bad
Interest cover0.8×Bad

Valuation

Fair value vs price0.6×Bad
EBIT / EV yield0.5%Bad

Profitability

Return on invested capital1.4%Bad
Operating margin2.3%Bad
stocksxray.com · page 2
XStocksXray
Charles River Laboratories International, Inc. (CRL)

Financials US$ millions, from SEC filings; last column is the last twelve months

Income statementFY21FY22FY23FY24FY25LTM
Revenue3,5403,9764,1294,0504,0153,999
Gross profit––––––
Operating income5906516172272590
Net income39148647522-144-238
Diluted EPS ($)7.609.489.220.20-2.91-4.87
Free cash flow532295365502518371
Gross margin––––––
Operating margin16.7%16.4%14.9%5.6%0.6%2.3%
Net margin11.0%12.2%11.5%0.5%−3.6%−6.0%
Balance sheetFY21FY22FY23FY24FY25LTM
Total assets7,0247,6038,1957,5287,1357,532
Cash241234277195214192
Total debt2,6642,7092,6502,2402,1372,625
Equity2,5352,9763,5973,4623,1652,840
Dividend per share ($)––––––

Revenue and net income US$ billions: navy revenue, teal net income

FY21FY22FY23FY24FY25

Margins blue gross, teal operating, brown net

-4%3%10%17%FY21FY22FY23FY24FY25

Latest quarters

Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026Jun 2026
Revenue ($M)9841,0321,0059949961,004
Growth vs a year earlier−2.7%+0.6%−0.5%−0.8%+1.2%−2.7%
Net income ($M)255254-277-15-1
Diluted EPS ($)0.501.061.10–-0.30-0.03
stocksxray.com · page 3
XStocksXray
Charles River Laboratories International, Inc. (CRL)

Peers in Life Sciences Tools & Services

CompanyX-Ray
CRL · Charles River Laboratories...22
MTD · Mettler Toledo Internation...50
A · Agilent Technologies, Inc.42
IQV · Iqvia Holdings Inc.42
TECH · BIO-TECHNE Corp40

Market Compass outlook for Health Care: Neutral (51/100). It blends regime history, macro sensitivity, momentum and valuation.

Returns

1 week−0.5%
1 month+6.6%
3 months+36.6%
6 months+63.2%
1 year+75.8%
3 years+52.3%
5 years−26.6%

Technical summary

DailyBullish10 bullish · 4 neutral · 2 bearish
WeeklyStrongly bullish11 bullish · 0 neutral · 1 bearish
MonthlyStrongly bullish7 bullish · 1 neutral · 0 bearish
50-day / 200-day average$288.88 / $215.10
52-week low / high$146.20 / $333.30
Classic pivot, support and resistanceS2 289.30 · S1 294.72 · P – · R1 307.20 · R2 314.26
stocksxray.com · page 4
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Charles River Laboratories International, Inc. (CRL)

Strengths

No check stands out as a clear strength against its sector.

Risks and weak spots

  • Free-cash-flow yield is weak against Health Care peers (2.6%).
  • Altman Z score is weak against Health Care peers (1.7×).
  • Piotroski F-Score is weak against Health Care peers (4 of 9).
  • Revenue growth (3y) is weak against Health Care peers (0.3%).
  • Growth consistency is weak against Health Care peers (20%).
  • Net debt / EBITDA is weak against Health Care peers (6.3×).
  • Interest cover is weak against Health Care peers (0.8×).
  • Fair value vs price is weak against Health Care peers (0.6×).

Latest SEC filings

DateFormItems
24 Sep 20268-K7.01,9.01
5 Aug 202610-Q
5 Aug 20268-K2.02,9.01
11 May 20268-K5.02,5.07,9.01
7 May 202610-Q
7 May 20268-K2.02,9.01
31 Mar 2026DEF 14A
25 Feb 20268-K7.01

How to read this report

Every number comes from SEC filings, end-of-day prices and the StocksXray models described on the methodology page. The X-Ray Score ranks each metric against the company's own sector. Fair value blends three models and carries a typical error of about 40%, so treat it as a range. Analyst ratings, price targets and earnings-call summaries are not part of this report. Educational research, not financial advice; read the disclaimer.

stocksxray.com · page 5 · generated 19 Oct 2026