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XStocksXray
Research report · 16 October 2026

Illumina, Inc. (ILMN)

Health Care · Life Sciences Tools & Services · US stock · price as of 16 Oct 2026

Key indicators

Price$262.54
52-week range$93.50 – $309.35
Market cap$40.2B
P/E (trailing)49.1×
EV / EBITDA46.5×
Free-cash-flow yield2.3%
Dividend yield–
Revenue (last 12 months)$4.5B
Revenue growth (3y a year)−1.8%
Operating margin19.6%
Return on invested capital19.6%
Net debt / EBITDA0.9×

Fair value

Blended fair value$127.23 range $121 – $134
Versus priceData under review+0% to fair value
Peer multiples$135.18
Fundamentals-adjusted multiple$128.48
10-year DCF (market-scaled)$118.04
Earnings power value (floor, not blended)n/m
Model uncertaintyHigh

X-Ray Score

39/ 100 · High confidence · ahead of 17% of sector peers
Valuation12
Growth30
Profitability56
Financial health63
Dividends–

Five-year price chart navy: price · brown: 200-day average · blue band: fair value range

49.78146241337433Fair value $1272021-102023-012024-042025-072026-10

Executive summary

Illumina makes instruments, chemicals and software used to read DNA at scale. Its sequencing systems and the single-use consumables that run on them are used in research, clinical testing, cancer and genetic disease diagnostics, and drug discovery. Customers are academic and government laboratories, pharmaceutical and biotechnology firms and clinical labs. The company is based in San Diego.

Illumina earns money from instrument placements and from ongoing consumables and services that run on its installed base. Revenue is $4.5 billion over the last twelve months, but revenue growth over three years is -1.8% a year. The operating margin is 19.6%, and the business earns a profit of 20% on the capital invested in it. The company carries net debt of 0.9 times EBITDA and pays no dividend.

StocksXray gives Illumina, Inc. an X-Ray Score of 39 out of 100 (high confidence), ahead of 17% of the S&P 500 stocks in its sector. Its strongest lens is financial health (63) and its weakest is valuation (12).

Our fair value blend is $127.23 (range $121.41 to $133.92). At $262.54 the stock trades 106% above that blend, so the label is "Data under review" with high model uncertainty. Fair value is a range, not a price target.

stocksxray.com · page 1
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Illumina, Inc. (ILMN)

Valuation history multiples at each fiscal year-end price; the last column uses today's price and the last twelve months

FY2022FY2023FY2023FY2024FY2025Now
Price$370.08$196.69$135.45$135.27$134.95$262.54
Market cap$55.9B$30.9B$21.4B$21.5B$21.1B$40.2B
P/E73.4×–––24.8×49.1×
EV / revenue12.3×6.7×4.8×5.1×4.9×9.1×
EV / EBITDA433.9×–––19.9×46.5×
Price / free cash flow165.8×291.3×75.6×30.3×22.6×43.1×
Free-cash-flow yield0.6%0.3%1.3%3.3%4.4%2.3%
Price / book5.2×4.7×3.7×9.1×7.7×14.2×
Dividend yield––––––

Fundamentals checklist ● 5 Good · ● 5 Average · ● 5 Bad · each check graded against the sector

Cash quality

Earnings backed by cash−4.1%Average
Free-cash-flow yield2.3%Bad

Risk models

Altman Z score2.9×Average
Piotroski F-Score8 of 9Good

Growth

Free-cash-flow growth (3y)106.3%Good
Revenue growth (3y)−1.8%Bad
Growth consistency40%Bad

Balance sheet

Current ratio1.8×Average
Net debt / EBITDA0.9×Good
Interest cover8.9×Average

Valuation

Fair value vs price0.5×Bad
EBIT / EV yield2.2%Bad

Profitability

Return on invested capital19.6%Good
Operating margin19.6%Average
Gross profitability44.9%Good
stocksxray.com · page 2
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Illumina, Inc. (ILMN)

Financials US$ millions, from SEC filings; last column is the last twelve months

Income statementFY22FY23FY23FY24FY25LTM
Revenue4,5264,5844,5044,3724,3434,493
Gross profit3,1542,9722,7442,8612,8702,983
Operating income-123-4,179-1,069-833807882
Net income762-4,404-1,161-1,223850825
Diluted EPS ($)5.04-28.00-7.34-7.695.455.35
Free cash flow337106283709931931
Gross margin69.7%64.8%60.9%65.4%66.1%66.4%
Operating margin−2.7%−91.2%−23.7%−19.1%18.6%19.6%
Net margin16.8%−96.1%−25.8%−28.0%19.6%18.4%
Balance sheetFY22FY23FY23FY24FY25LTM
Total assets15,21712,25210,1116,3036,6446,650
Cash1,2322,0111,0481,1271,4181,040
Total debt9931,9871,4891,9891,9891,991
Equity10,7406,5995,7452,3732,7232,838
Dividend per share ($)––––––

Revenue and net income US$ billions: navy revenue, teal net income

FY22FY23FY23FY24FY25

Margins blue gross, teal operating, brown net

-96%-41%14%70%FY22FY23FY23FY24FY25

Latest quarters

Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026Jun 2026
Revenue ($M)1,0411,0591,0841,1591,0911,159
Growth vs a year earlier−3.3%−4.8%+0.4%+5.0%+4.8%+9.4%
Net income ($M)131235150334134207
Diluted EPS ($)0.821.490.98–0.871.35
stocksxray.com · page 3
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Illumina, Inc. (ILMN)

Peers in Life Sciences Tools & Services

CompanyX-Ray
ILMN · Illumina, Inc.39
MTD · Mettler Toledo Internation...50
A · Agilent Technologies, Inc.42
IQV · Iqvia Holdings Inc.42
TECH · BIO-TECHNE Corp40

Market Compass outlook for Health Care: Neutral (51/100). It blends regime history, macro sensitivity, momentum and valuation.

Returns

1 week−5.6%
1 month+7.1%
3 months+42.2%
6 months+95.2%
1 year+182.3%
3 years+95.7%
5 years−34.2%

Technical summary

DailyBullish9 bullish · 2 neutral · 5 bearish
WeeklyStrongly bullish11 bullish · 0 neutral · 1 bearish
MonthlyStrongly bullish7 bullish · 0 neutral · 1 bearish
50-day / 200-day average$233.92 / $169.65
52-week low / high$93.50 / $309.35
Classic pivot, support and resistanceS2 251.85 · S1 257.20 · P – · R1 269.95 · R2 277.35
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Illumina, Inc. (ILMN)

Strengths

  • Return on invested capital of 19.6% is ahead of 74% of its sector peers.
  • Net debt is only 0.9× EBITDA, ahead of 72% of its sector peers.
  • Piotroski F-Score of 8 out of 9: most of the nine accounting health tests pass.

Risks and weak spots

  • Free-cash-flow yield is weak against Health Care peers (2.3%).
  • Revenue growth (3y) is weak against Health Care peers (−1.8%).
  • Growth consistency is weak against Health Care peers (40%).
  • Fair value vs price is weak against Health Care peers (0.5×).
  • EBIT / EV yield is weak against Health Care peers (2.2%).

Latest SEC filings

DateFormItems
13 Oct 20268-K1.01,2.03,9.01
17 Aug 20268-K8.01,9.01
13 Aug 20268-K1.01,1.02,2.03,9.01
12 Aug 20268-K8.01,9.01
7 Aug 20268-K8.01,9.01
31 Jul 202610-Q
30 Jul 20268-K2.02,9.01
23 Jun 20268-K5.02

How to read this report

Every number comes from SEC filings, end-of-day prices and the StocksXray models described on the methodology page. The X-Ray Score ranks each metric against the company's own sector. Fair value blends three models and carries a typical error of about 40%, so treat it as a range. Analyst ratings, price targets and earnings-call summaries are not part of this report. Educational research, not financial advice; read the disclaimer.

stocksxray.com · page 5 · generated 19 Oct 2026